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    Книжкова полиця /Природничі науки/S,N-modified aminothiols as antioxidants and potential anti-radiation agents (англ. мовою)

    LIST OF ABBREVIATIONS
    INTRODUCTION
    CHAPTER 1. KNOWN RADIOPROTECTORS AND ANTIOXIDANTS. THEIR MECHANISM OF ACTION
    CHAPTER 2. MATERIALS AND RESEARCH METHODS
    Used material
    Physicochemical methods of analysis
    Computer prediction of compounds' biological activity
    Study of toxicological effects of compounds on different taxonomic groups
    Antioxidant activity determination
    Study of antitumor activity
    Study of radioprotective activity
    Statistical data processing
    CHAPTER 3. COMPUTER PREDICTION OF BIOLOGICAL ACTIVITY
    Relationship between chemical structure and predicted biological activity among S-(2-methylquinolin-4-yl)-L-cysteine derivatives
    Relationship between chemical structure and predicted biological activity among β-(2-methylquinolin-4-ylthio)-propionic acid derivatives
    Relationship between chemical structure and predicted biological activity of S-(2-methylquinolin-4-yl)-cysteamine derivatives
    Determination of promising compounds and research directions of their biological action in a number of S-(2-methylquinolin-4-yl)-L-cysteine derivatives and their structural analogs
    CHAPTER 4. SYNTHESIS AND PHYSICOCHEMICAL PROPERTIES
    Synthesis and physicochemical properties of S-(2-methylquinolin-4-yl)-L-cysteines derivatives
    Synthesis and physicochemical properties of β-(2-methylquinolin-4-ylthio)-propionic acids derivatives
    Synthesis and physicochemical properties of S-(2-methylquinolin-4-yl)-cysteamines derivatives
    Experimental part
    CHAPTER 5. STUDY OF CHEMICAL STRUCTURE AND BIOLOGICAL ACTIVITY RELATIONSHIP
    Antimicrobial activity
    Cytotoxicity (phytotoxicity)
    Acute toxicity
    In vitro antiradical activity
    Antitumor activity
    CHAPTER 6. ANTIOXIDANT AND ANTIRADICAL ACTIVITY AS A PREREQUISITE OF RADIOPROTECTIVE ACTION
    Determination of antiradical and antioxidant activity of compounds by pulse voltammetry
    Radioprotective activity
    CONCLUSIONS
    ATTACHMENTS
    REFERENCES

    S,N-modified aminothiols as antioxidants and potential anti-radiation agents (англ. мовою)